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P6101
Sigma
Anti-Platelet-Derived Growth Factor antibody produced in goat
IgG fraction of antiserum, lyophilized powder
| Synonym: | Anti-PDGF |
| MDL number: | MFCD00165456 |
Description
| Immunogen | natural human PDGF. |
| Preparation Note | Purified using protein G. |
| Specificity | The antibody will neutralize the biological activity of natural human PDGF, recombinant human PDGF-AB, PDGF-AA and PDGF-BB and natural porcine PDGF-BB. |
| Physical form | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) with 5% trehalose. |
Properties
| antibody form | IgG fraction of antiserum |
| clone | (polyclonal) |
| form | lyophilized powder |
| species reactivity | human |
| application(s) | immunoblotting: suitable |
| indirect ELISA: suitable | |
| neutralization: suitable | |
| Gene Information | human ... PDGFA(5154), PDGFB(5155) |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
References
| reference | Mastro, A., and Mercer, R., Cytokines secreted by bone-metastatic breast cancer cells alter the expression pattern of f-actin and reduce focal adhesion plaques in osteoblasts through PI3K. Exp. Cell Res. 310, 270-281, (2005) Abstract |
| Sawcer, D., et al., Mechanism of Human Dermal Fibroblast Migration Driven by Type I Collagen and Platelet-derived Growth Factor-BB Mol. Biol. Cell 15, 294-309, (2004) Abstract |
